Immunoreactive antigens of hepatitis e virus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/51 (2006.01) A61K 39/29 (2006.01) C07K 14/08 (2006.01) C07K 14/085 (2006.01) C07K 19/00 (2006.01) C12N 9/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2170521

The present invention relates generally to molecules such as peptides, polypeptides and proteins which carry epitopes and in particular B cell epitopes from antigenic proteins encoded by Hepatitis E Virus. These molecules are selectively immunoreactive to convalescent and/or acute phase circulating antibodies to the Hepatitis E Virus and are useful in the development of diagnostic therapeutical and prophylactic agents for Hepatitis E Virus.

L'invention a trait d'une façon générale à des molécules telles que des peptides, des polypeptides ou des protéines porteurs d'épitopes et en particulier d'épitopes de cellules B de protéines antigènes codées par le virus de l'hépatite E. Ces molécules, sélectivement immunoréactives vis à vis des anticorps du virus de l'hépatite E en phase de convalescence ou aiguë, servent à la mise au point d'agents diagnostiques, thérapeutiques et prophylactiques du virus de l'hépatite E.

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