Immunoreactive reagents employing dihydrofolate reductase

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 51/08 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 9/06 (2006.01) G01N 33/531 (2006.01) G01N 33/532 (2006.01) G01N 33/535 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2151614

This invention describes a non-radioactive targeting immunoreagent comprised of the residue of a proteinaceous active site of a dihydrofolate reductase enzyme (DHFR), a linking group, and the residue of an immunoreactive material together with a radioactive delivery agent comprised of the residue of a ligand which has an affinity for non-covalent binding to said DHFR receptor moiety, a linking group, and the residue of a radioactive agent. This invention also describes a non-radioactive targeting immunoreagent comprised of the residue of a ligand which has an affinity for non-covalent binding to a DHFR proteinaceous active site receptor moiety, a linking group, and the residue of an immunoreactive material together with a radioactive delivery agent comprised of the residue of a DHFR proteinaceous active site receptor moiety, a linking group, and a radioactive agent. These compositions comprise useful systems for the production of an amplification of delivery of the radioactive agent to tumor sites in the therapy and diagnostic imaging of cancer.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Immunoreactive reagents employing dihydrofolate reductase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunoreactive reagents employing dihydrofolate reductase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoreactive reagents employing dihydrofolate reductase will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1431837

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.