G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/544 (2006.01) G01N 33/543 (2006.01) G01N 33/553 (2006.01)
Patent
CA 2055117
Ref. 4090/2 16 Abstract The immunosensory transducer for surface plasmoresonance has a gold carrier, a two-dimensional matrix in the form of a monomolecular organic intermediate layer on this surface and a ligand or antiligand layer immobilized on this. The transducer in accordance with the invention is considerably simpler to produce than known transducers having a three-dimensional matrix. For the production, a monomolecular layer of alkyl derivatives with sulphur-containing groups is applied to the gold surface by spontaneous chemisorption and subsequently a ligand or antiligand suitable for the desired immune detection is immobilized on this layer.
Barner Richard
Huber Walter
Hubscher Josef
Schlatter Daniel
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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