Immunostimulatory oligonucleotides

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 39/29 (2006.01)

Patent

CA 2745096

The invention relates to immunostimulatory oligonucleotides and methods of using immunostimulatory oligonucleotides to induce an antigen-specific immune response. The invention further relates to a vaccine that comprises an immunostimulatory oligonucleotide and an antigen, and comprises a pharmaceutically acceptable carrier. The immunostimulatory oligonucleotides of the invention, in some embodiments, include one or more modified linkage(s).

Linvention concerne des oligonucléotides immunostimulants et des méthodes dutilisation doligonucléotides immunostimulants pour induire une réponse immunitaire spécifique de lantigène. Linvention concerne en outre un vaccin qui renferme un oligonucléotide immunostimulant et un antigène et qui comprend un support pharmaceutiquement acceptable. Les oligonucléotides immunostimulants de linvention, dans certains modes de réalisation, comprennent une ou plusieurs liaisons modifiées.

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