A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/711 (2006.01) A61K 31/7105 (2006.01) A61P 31/12 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2402259
The invention provides methods of suppression, prevention, and/or treatment of infection by viruses. A polynucleotide comprising an immunostimulatory sequence (an "ISS") is administered to an individual who is at risk of being exposed to, has been exposed to or is infected with a virus. The ISS- containing polynucleotide is administered without any antigens of the virus. Administration of the ISS-containing polynucleotide results in reduced incidence and/or severity of one or more symptoms of virus infection.
Cette invention concerne des méthodes destinées à supprimer, prévenir et/ou traiter des infections virales. A un individu qui risque d'être exposé, a été exposé ou est infecté par un virus, on administre un polynucléotide renfermant une séquence immunostimulatoire. Le polynucléotide qui renferme ladite séquence est administré sans antigène du virus. L'administration de cette séquence polynucléotidique immunomodulatoire se traduit par une baisse de l'incidence et/ou une moindre gravité de l'un ou de plusieurs symptômes de l'affection virale.
Eiden Joseph J. Jr.
Van Nest Gary
Borden Ladner Gervais Llp
Dynavax Technologies Corporation
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