A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 31/7088 (2006.01)
Patent
CA 2412026
The present invention provides immunological compositions and methods relating to immunostimulatory intra-strand DNA/RNA hybrid oligonucleotides (HDRs), optimally encoding one or more CpG motif, which may be an unmethylated CpG motif. Administration of these compounds, alone or in the context of one or more target antigens, promotes innate and antigen specific immunities.
L'invention concerne des compositions et des méthodes immunologiques relatives à des oligonucléotides hybrides ARN/ADN intrabrin immunostimulateurs (HDR), codant optimalement pour un ou plusieurs motifs CpG, qui peuvent être un motif CpG non méthylé. L'administration de ces composés, seuls ou dans le contexte d'un ou de plusieurs antigènes cibles, stimule des immunités naturelles et spécifiques d'antigènes.
Flora Michael
Klinman Dennis M.
Mond James J.
Biosynexus Incorporated
Departmen T. Of Health And Human Services The United States Of America As Represented By The Secretary
Henry M. Jackson Foundation For The Advancement Of Military Medi
LandOfFree
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