Immunosuppressant

C - Chemistry – Metallurgy – 07 – C

Patent

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167/245, 167/261

C07C 229/22 (2006.01) A61K 31/195 (2006.01) A61K 31/365 (2006.01) C07D 307/33 (2006.01)

Patent

CA 2011045

ABSTRACT The present invention relates to an immunosuppressive agent which comprises at least one compound selected from the compounds of formula Image wherein R represents a hydrogen atom or an acyl, Y represents carbonyl or hydroxymethylene and ----- represents a single bond or a double bond and their lactones, in an effective amount and a pharmaceutically acceptable carrier; a method of prophylaxis and therapy for suppressing rejection or autoimmune diseases which comprises administering the above-mentioned compound or its lactone in an effective amount; and a novel compound of formula Image or its lactone.

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