Immunosuppressant compounds, methods and uses related thereto

Details Immunosuppressant compounds, methods and uses related thereto Immunosuppressant compounds, methods and uses related thereto

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/03 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 39/00 (2006.01) A61P 37/06 (2006.01) C07K 4/00 (2006.01) C07K 5/065 (2006.01) C07K 5/087 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C07K 7/02 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2479939

The present invention relates to compositions and methods for suppressing an immune response, e.g, by inhibiting class II MHC- mediated activation of T cells. The subject compounds and methods may be used to treat or prevent disorders such as rheumatoid arthritis and/or multiple sclerosis.

La présente invention concerne des compositions et des méthodes permettant de supprimer une réponse immunitaire, par exemple, par inhibition d'une activation à médiation MHC de classe II de lymphocytes T. Les composés et les méthodes de cette invention peuvent être utilisés pour traiter ou prévenir des troubles, tels que la polyarthrite rheumatoïde et/ou la sclérose en plaques.

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