Immunosuppressive-activity potentiating compositions

A - Human Necessities – 61 – K

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A61K 31/665 (2006.01) A61K 38/13 (2006.01)

Patent

CA 2195371

According to the present invention, there are provided immunosuppressive-activity potentiating compositions which comprise a phosphoric acid diester compound represented by the following formula [I]: (see fig. I) [I] (R1 and R3 are the same or different and represent individually a hydrogen atom or methyl group) or its pharmacologically acceptable salt, and the immunosuppressive-activity potentiating compositions can suppress effectively acute rejection after transplanation.

a présente invention consiste en compositions activant l'activité immunosuppressive, constituées d'un composé de diester d'acide phosphorique représenté par la formule suivante [I]: (voir fig. I) [I] (R1 et R3 sont semblables ou différents et représentent chacun un atome d'hydrogène ou un groupe méthyle) ou par son sel acceptable sur le plan pharmacologique; ces compositions peuvent supprimer efficacement le rejet aigu après une greffe ou une transplantation

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