A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61K 38/13 (2006.01) A61P 37/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2408889
The invention features a composition containing an immunophilin-binding compound and a ginkgolide compound, methods of inducing immunosuppression, and methods of screening for immunosuppressive ginkgolide compounds. The ginkgolide compound is selected from the group consisting of a phosphodiesterase inhibitor, a platelet activating factor (PAFR) antagonist, and a free radical scavenger.
Cette invention se rapporte à une composition contenant un composé de fixation d'immunophiline et un composé de ginkgolide, à des procédés permettant d'induire l'immunosuppression et à des procédés de criblage de composés de ginkgolide immunosuppresseurs. Le composé de ginkgolide est choisi dans le groupe constitué par un inhibiteur de phosphodiestérase, un antagoniste du facteur d'activation des plaquettes (PAFR) et un piégeur de radicaux libres.
Haines David
Mahmoud Fadia F.
Tosaki Arpad
Haines David
Mahmoud Fadia F.
Mbm Intellectual Property Law Llp
Tosaki Arpad
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