Immunotherapeutic imides/amides and their use for reducing...

Details Immunotherapeutic imides/amides and their use for reducing... Immunotherapeutic imides/amides and their use for reducing...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/40 (2006.01) A61K 31/4035 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) C07D 209/44 (2006.01) C07D 209/46 (2006.01) C07D 209/48 (2006.01)

Patent

CA 2208672

Novel imide/amide ethers are inhibitors of tumor necrosis factor a and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 1-Phthalimido-l-(3',4'- dimethoxyphenyl)propan-1-ol.

Des éthers nouveaux d'imides/amides inhibent le facteur alpha de nécrose de tumeurs et sont utiles pour combattre la cachexie, le choc endotoxique et la réplication rétrovirale. Un mode typique de réalisation est 1-phtalimido-1-(3',4'-diméthoxyphényl)propan-1-ol.

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