Immunotherapeutic method to prevent islet cell rejection

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2410786

A method for the prevention or reversal of islet cell transplant rejection, or for therapy for autoimmune diseases, is provided comprising administering compounds such as monoclonal antibodies, that bind specifically to CD40L and the CD4 receptor.

L'invention concerne un procédé destiné à la prévention ou à l'inversion d'un rejet de transplantation de cellule insulaire, ainsi qu'au traitement de maladies auto-immunes, consistant à administrer des composés tels que des anticorps monoclonaux se fixant spécifiquement au CD40L et au récepteur CD4.

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