Immunotherapeutic methods and compositions

A - Human Necessities – 61 – K

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Details

A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/785 (2006.01)

Patent

CA 2404325

This invention relates to methods and compositions introducing chemical entities into antigen presenting cells. The resulting presentation of said antigens on the surface of the antigen presenting cells gives an effect on the immune system. The invention also relates to the resulting modified antigen presenting cells and pharmaceutical compositions containing these cells. The invention discloses new understandings in adjuvancy and adjuvant preparations, including a series of related peptides and phospholipid vesicles incorporating said peptides.

Cette invention concerne des méthodes et des compositions introduisant des entités chimiques dans des cellules présentatrices d'antigènes. La présentation résultante desdits antigènes sur la surface des cellules présentatrices d'antigènes produit un effet sur le système immunitaire. L'invention concerne également les cellules présentatrices d'antigènes modifiées qui en résultent et les compositions pharmaceutiques contenant lesdites cellules. L'invention concerne en outre de nouvelles connaissances en matière d'adjuvance et de préparations adjuvantes, y compris une série de peptides et de vésicules phospholipides correspondants incorporant lesdits peptides.

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