Immunotherapy using interleukin 13 receptor subunit alpha 2

A - Human Necessities – 61 – K

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Details

A61K 39/00 (2006.01) A01N 43/04 (2006.01) A61K 39/395 (2006.01) C07K 1/00 (2006.01) C07K 14/715 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2398136

A method for stimulating an immune response against IL-13R.alpha.2 in a subject having or at risk for developing a disease having cells expressing IL- 13R.alpha.2 includes the steps of formulating the anti-cancer vaccine outside of the subject and administering the vaccine to the subject in an amount sufficient to stimulate an immune response against IL-13R.alpha.2 in a subject. A compostion for stimulating an immune response against IL- 13R.alpha.2 in a subject having or at risk for developing a disease having cells expressing IL-13R.alpha.2 includes an isolated agent that can stimulate immune response against IL-13.alpha.2.

L'invention concerne une méthode pour stimuler une réponse immunitaire contre IL-13R.alpha.2 chez un sujet ayant ou présentant le risque de développer une maladie où des cellules expriment IL-13R.alpha.2. Ladite méthode comprend la formulation du vaccin anti-cancer à l'extérieur du sujet et l'administration du vaccin au sujet dans une quantité suffisante pour stimuler une réponse immunitaire contre IL-13R.alpha.2 chez celui-ci. L'invention concerne également une composition pour stimuler une réponse immunitaire contre IL-13R.alpha.2 chez un sujet ayant ou présentant le risque de développer une maladie où des cellules expriment IL-13R.alpha.2a. Ladite composition comprend un agent isolé susceptible de stimuler une réponse immunitaire contre IL-13.alpha.2.

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