Immunotoxins directed against malignant cells

Details Immunotoxins directed against malignant cells Immunotoxins directed against malignant cells

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 47/48 (2006.01) C07K 14/46 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2288232

The present invention relates to immunotoxins, that effectively kill malignant cells having a given surface marker and nucleic acid constructs encoding them. These reagents comprise a toxic moiety that is derived from a Rana pipiens protein having ribonucleolytic activity linked to an antibody capable of specific binding with a chosen tumor cell.

Cette invention concerne des immunotoxines tuant, de manière satisfaisante, des cellules malignes possédant un marqueur de surface donnée et des produits de recombinaison d'acide nucléique les codant. Ces réactifs comportent une fraction toxique dérivée d'une protéine de grenouille léopard (Rana pipiens) à activité ribonucléolytique liée à un anticorps capable de liaison spécifique avec une cellule tumorale sélectionnée.

Affiliated with

Also associated with

Rating

Immunotoxins directed against malignant cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunotoxins directed against malignant cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunotoxins directed against malignant cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1415558