Impdh2 snp associated with acute rejection

Details Impdh2 snp associated with acute rejection Impdh2 snp associated with acute rejection

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2611005

The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in intron 7 of the IMPDH2 gene, optionally in combination with polymorphisms of the MDRl and IL 10 genes which were found to be associated with this disease.

L'invention concerne un procédé de prédiction de rejet de transplantation rénale aigu par détection d'un polymorphisme dans un intron 7 du gène IMPDH2, éventuellement en combinaison avec des polymorphismes des gènes MDR1 et IL 10 dont on a découvert qu'ils étaient associés à cette maladie.

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