Implant device release agents and methods of using same

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/54 (2006.01) A61L 27/14 (2006.01) A61L 27/50 (2006.01) B29C 33/62 (2006.01)

Patent

CA 2685397

Medical implant devices are prepared from a polymeric material and a release agent, where the device is a molded, reservoir implant, and the release agent has a molecular weight (MW) of at least 1000. The release agent may be a non-ionic surfactant such as Brij 35, polyoxyetheylene(20)sorbitan trioleate, Tween 20, Tween 80, vitamin E TPGS, and a mixture of any two or more thereof. Hydrated implants may have a surface area of about 500 mm or greater.

La présente invention concerne des implants à usage médical préparés à partir d'un matériau polymère et d'un agent de démoulage, le dispositif étant un implant à réservoir moulé et l'agent de démoulage ayant un poids moléculaire (MW) d'au moins 1000. L'agent de démoulage peut être un tensioactif non ionique, tel que Brij 35, un trioléate de polyoxyéthylène(20)sorbitan, Tween 20, Tween 80, la vitamine E TPGS, et un mélange de deux quelconques d'entre eux ou plus. Les implants hydratés peuvent avoir une aire spécifique d'environ 500 mm ou plus.

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