Implant for percutaneous sampling of serous fluid and for...

A - Human Necessities – 61 – M

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A61M 37/00 (2006.01) A61M 39/02 (2006.01) A61M 1/16 (2006.01) A61M 31/00 (2006.01)

Patent

CA 1294843

ABSTRACT An implant comprises interconnected compartments with inlet and outlet and can be used for sampling of entered serous fluid or to hold drug concentrate for selective delivery, if desired. The compartments are formed by sealing around porous foam rings between a top and a bottom layer of biocompatible elastic membrane with a polymer paste which sets to form a rubbery shell. The top membrane layer over the compartment is punctured to create a small resealable channel. Upon subcutaneous implantation, serous fluid under hydrostatic pressure seeps into the interior through the puncture orifice. The entered fluid may be withdrawn by an hypodermic syringe through the rubbery side wall to obtain serum-borne bioactive materials. If a drug concentrate is included, the entered fluid will dissolve some of the drug therein. When delivery is required, external sidewise compression of the elastic compartment over the skin fold expels the drug containing solution therein through the orifice.

563476

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