Implant tissue

Details Implant tissue Implant tissue

A - Human Necessities

61

L

167/322

A61L 27/00 (2006.01) A61L 27/36 (2006.01) C08H 1/06 (2006.01)

Patent

CA 1261760

ABSTRACT Implant Tissue A collagenous fibrous tissue preparation of human or animal origin is described which is suitable for homo- or hetero transplantation either as a temporary dressing or as a permanent implant. The fibrous tissue preparation is preferably in sheet form and is prepared by a process which results in the fibrous tissue being substantially free of non-fibrous tissue proteins, glycoproteins, cellular elements, lipids and lipid residues. This process involves treatment of the fibrous tissue with a diisocyanate which unlike earlier processes using, for example, dialde- hyde treatment agents, provides a fibrous tissue preparation which is non-cytotoxic and is stable to endogenous proteolytic enzymes. The preparation and use of the fibrous tissue is also described.

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