A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/50 (2006.01) A61K 35/12 (2006.01) A61K 35/39 (2006.01)
Patent
CA 2109085
An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to main- tain the cells, and a permselective, biocompatible, peripheral region free of the isolated cells, which immunoisolates the core yet provides for the delivery of the secreted product or metabolic function to the individual. The vehicle is particularly well-suited to delivery of insulin from immunoisolated islets of Langerhans, and can also be used advantageously for delivery of high molecu- lar weight products, such as products larger than IgG. A method of making a biocompatible, immunoisolatory implantable vehi- cle, consisting in a first embodiment of a coextrusion process, and in a second embodiment of a stepwise process. A method for isolating cells within a biocompatible, immunoisolatory implantable vehicle, which protects the isolated cells from attack by the immune system of an individual in whom the vehicle is implanted. A method of providing a needed biological product or meta- bolic function to an individual, comprising implanting into the individual an immunoisolatory vehicle containing isolated cells which produce the product or provide the metabolic function.
Aebischer Patrick
Christenson Lisa
Dionne Keith E.
Emerich Dwaine F.
Gentile Frank T.
Brown University Research Foundation
Smart & Biggar
LandOfFree
Implantable biocompatible immunoisolatory vehicle for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Implantable biocompatible immunoisolatory vehicle for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Implantable biocompatible immunoisolatory vehicle for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1385842