Implantable biological tissue and process for preparation...

A - Human Necessities – 01 – N

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167/104, 167/327

A01N 1/02 (2006.01) A61F 2/24 (2006.01) A61L 27/36 (2006.01)

Patent

CA 1221641

ABSTRACT OF THE INVENTION A process for the preparation of implantable biological tissue and in particular bioprosthetic heart valves, which are prone to calcification after implantation. The process includes treatment of tissue with a hypophosphated isotonic solution prior to implantation which has been found effective in reducing calcification of the implanted tissue. The solution contains a physiologically acceptable salt of a divalent cation other than calcium.

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