Implantable bioresorbable membrane and method for the...

A - Human Necessities – 61 – L

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A61L 27/00 (2006.01) A61F 2/02 (2006.01) A61L 31/06 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2219995

An implantable bioresorbable membrane for the separation and regeneration of tissue in a defect site and augmentation of tissues surrounding other implants comprises: (a) porous bioresorbable polymer matrix made of a bioresorbable polymer selected from the group consisting of polylactic acid, poly(lactic-co- glycolic acid), polycarprolactone, polyparadioxanone, polytrimethylene carbonate and a mixture thereof; and (b) a reinforcing fabric made of bioresorbable fibers embedded in said matrix, and is produced by preparing a fabric as a support from bioresorbable fibrous materials, coating the fabric with a solution containing a bioresorbable polymer and a pore forming agent, and treating the coated fabric to generate pores.

Membrane biorésorbable implantable servant à séparer et régénérer des tissus situés dans un endroit défectueux. Cette membrane est constituée d'un tissu tissé ou tricoté formé de fibres biorésorbables et d'un film polymère biorésorbable/biocompatible poreux déposé sur les fibres. Pour produire la membrane biorésorbable implantable de cette invention, on prépare un tissu servant de support, à partir de matières fibreuses biorésorbables, on recouvre le tissu avec une solution contenant un polymère biorésorbable/biocompatible et un agent porogène, on traite le tissu enduit pour générer des pores puis on gaufre le tissu enduit.

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