Implantable controlled release device to deliver drugs...

A - Human Necessities – 61 – M

Patent

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Details

A61M 31/00 (2006.01) A61F 9/00 (2006.01) A61K 9/00 (2006.01) A61K 9/24 (2006.01) A61K 9/32 (2006.01)

Patent

CA 2230947

A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desired local or systemic physiological or pharmacological effect by surgically implanting such a sustained release drug delivery device into a mammal in need of treatment is also disclosed.

La présente invention concerne un dispositif simple et implantable de libération continue de médicaments. Ce dispositif est constitué d'une partie interne renfermant une quantité efficace d'un agent faiblement soluble, et enduit d'une couche de polymère non bio-érodable perméable à l'agent faiblement soluble. L'invention concerne également un procédé applicable pour le traitement d'un mammifère chez lequel on recherche un effet physiologique ou pharmacologique local ou systémique spécifique, par implantation chirurgicale, chez le mammifère nécessitant un tel traitement, un tel dispositif d'administration à libération continue de médicaments.

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