A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/36 (2006.01) A61L 27/54 (2006.01) A61L 31/00 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2607913
Described are materials and methods for inhibiting the formation of tissue adhesions. In one aspect, a prosthetic tissue support mesh, and especially such a mesh comprised of a remodelable material that promotes tissue ingrowth, incorporates an effective amount of an anti-inflammatory compound such as a non-steroidal anti- inflammatory drug (NSAID) to inhibit the formation of tissue adhesions to the mesh and/ or to surrounding tissues when implanted in a patient. Also described are materials and methods for increasing the length of persistence of implanted resorbable materials, and especially implanted bioremodelable materials, using an anti -inflammatory compound such as an NSAID.
L'invention concerne des matériaux et des méthodes servant à empêcher la formation d'adhérences tissulaires. Dans un aspect, un treillis de support de tissus prothétiques et particulièrement un treillis composé d'un matériau remodelable favorisant la croissance interne du tissu, incorpore une quantité efficace d'un composé anti-inflammatoire, tel qu'un médicament anti-inflammatoire non stéroïde (NSAID) permettant d'inhiber la formation d'adhérences tissulaires sur le treillis et/ou d'entourer les tissus quand ils sont implantés chez un patient. L'invention concerne également des matériaux et des méthodes servant à augmenter la longévité de matériaux résorbables implantés et, plus particulièrement, de matériaux bioremodelables implantés, au moyen d'un composé anti-inflammatoire, tel qu'un NSAID.
Hiles Michael C.
Hodde Jason P.
Janis Abram D.
Cook Biotech Incorporated
Smart & Biggar
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