Implantable materials having engineered surfaces and method...

Details Implantable materials having engineered surfaces and method... Implantable materials having engineered surfaces and method...

A - Human Necessities

61

L

A61L 27/50 (2006.01) A61F 2/06 (2006.01) A61F 2/28 (2006.01) A61L 27/06 (2006.01) B05D 3/06 (2006.01) C12N 11/14 (2006.01)

Patent

CA 2499976

Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.

L'invention concerne des matériaux implantables comprenant des motifs définis de zones d'affinité destinées à la fixation des cellules endothéliales et à la migration dirigée des cellules endothéliales à travers la surface du matériau. Ces zones d'affinité comportent des zones ayant subi une modification photochimique, ainsi que des éléments physiques formant des motifs à la surface du matériau, présentant une affinité pour la fixation et la migration des cellules endothéliales supérieure à celle des zones restantes de la surface du matériau.

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