Implantable mems medicine delivery system

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61M 5/142 (2006.01) A61M 31/00 (2006.01) A61M 35/00 (2006.01)

Patent

CA 2494198

A medicine delivery system (10) implantable into a human or animal body includes a medicine delivery unit (14) and a control unit (12). A membrane (26) seals the delivery opening (22) of a medicine compartment (18) and is pre- stressed by an amount less than the predetermined elastic deformation and rupture point limits of the membrane (26). A release element (28) associated with compartment (18) causes the membrane (26) to be stressed beyond the deformation and rupture point limits in response to a control signal (78). Release element (28) ruptures the membrane (26) along a predetermined rupture pattern to permit a first membrane portion (35), forming a hinged lid, to separate from a second membrane portion (37) along the predetermined rupture pattern while remaining attached to the second membrane portion at a hinge (39).

L'invention concerne un système d'administration de médicament (10), implantable chez l'homme ou chez un animal, comprenant une unité d'administration de médicament (14) et une unité de commande (12). Une membrane (26) scelle l'orifice d'administration (22) d'un compartiment contenant le médicament (18), cette membrane étant précontrainte d'une quantité inférieure à ses limites de déformation élastique et de point de rupture. Un élément de libération (28) associé au compartiment (18) permet de contraindre la membrane (26) à dépasser ses limites de déformation et de point de rupture en réponse à un signal de commande (78). L'élément de libération (28) rompt la membrane (26) selon une structure de rupture déterminée afin de permettre à une première portion de la membrane (35), formant un couvercle pivotant, de se séparer d'une seconde portion de la membrane (37) selon la structure de rupture déterminée, tout en restant attachée à cette seconde portion de membrane au point de pivot (39).

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