Implantable ocular drug delivery device and methods

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61F 9/00 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01) A61L 27/00 (2006.01)

Patent

CA 2743824

The present invention provides implantable ocular drug delivery devices. Generally, the devices have a distal por-tion with a coil shaped body member and a proximal portion which contacts the sclera. In one aspect, the coil-shaped body mem-ber includes a unique configuration including two coiled portions with different pitches, which improves insertion of the device into the eye. In another aspect, the device has a proximal portion that includes a unique cap configuration having a concave distal face that improves stabilization of the device in the eye. In another aspect, the device includes a transitional portion between the cap and the coil-shaped body member that also improves stabilization of the device in the eye. The invention also provides meth-ods for inserting the medical device into the eye, and methods for the treatment of an ocular condition.

Cette invention concerne des dispositifs implantables pour administration dun médicament ophtalmique. De façon générale, ces dispositifs comportent une partie distale munie dun élément principal de forme hélicoïdale et une partie proximale en contact avec la sclérotique. Selon un aspect, lélément hélicoïdal a la particularité de posséder deux parties hélicoïdales à pas différents, ce qui améliore linsertion du dispositif dans lil. Selon un autre aspect, le dispositif présente une partie proximale dotée dune coiffe originale avec une face distale concave permettant de mieux stabiliser le dispositif dans lil. Selon un autre aspect encore, le dispositif comporte entre la coiffe et lélément hélicoïdal une partie de transition qui améliore elle aussi la stabilisation du dispositif dans lil. Sont également décrites des techniques dinsertion du dispositif médical dans lil et des méthodes de traitement de pathologies oculaires.

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