Implantable or insertable medical devices containing...

A - Human Necessities – 61 – L

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Details

A61L 27/34 (2006.01) A61L 27/18 (2006.01) A61L 29/06 (2006.01) A61L 29/08 (2006.01) A61L 31/06 (2006.01) A61L 31/10 (2006.01)

Patent

CA 2534318

Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region, which controls the release of the therapeutic agent upon administration to a patient. The polymeric release region further comprises a silicone copolymer that contains a plurality of siloxane units and a plurality of non-siloxane units. Also described are methods for administering a therapeutic agent to a patient using the above implantable or insertable medical devices as well as methods of making the above devices.

L'invention concerne des dispositifs médicaux pouvant être implantés ou insérés. Lesdits dispositifs médicaux comprennent (a) un agent thérapeutique et (b) une région de libération polymère, laquelle régule la libération de l'agent thérapeutique lors de l'administration à un patient. La région de libération polymère comprend de plus, un copolymère silicone contenant une pluralité d'unités de siloxanes et une pluralité d'unités non siloxane. L'invention concerne également des procédés pour administrer un agent thérapeutique à un patient, au moyen des dispositifs médicaux pouvant être insérés ou implantés ainsi que des procédés pour fabriquer lesdits procédés.

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