Implantable or insertable medical devices having optimal...

A - Human Necessities – 61 – L

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A61L 27/34 (2006.01) A61L 27/26 (2006.01) A61L 27/50 (2006.01) A61L 31/10 (2006.01)

Patent

CA 2611482

An implantable or insertable medical device is provided that contains at least one polymeric region which comes into contact with a subject upon implantation or insertion of the device into the subject. The polymeric region(s) contain at least one bulk polymer moiety and at least one surface-active polymer moiety that (a) is covalently attached to the bulk polymer moiety/moieties or admixed with the bulk polymer moiety/moieties and (b) is provided in an amount that is effective in providing the polymeric region(s) with a critical surface energy that is between 20 dynes/cm and 30 dynes/cm upon implantation or insertion of the device into the subject.

L'invention concerne un dispositif médical implantable ou insérable qui contient au moins une région polymère destinée à entrer en contact avec un sujet après l'implantation ou l'insertion du dispositif dans le sujet. La ou les région(s) polymère(s) contiennent au moins une fraction polymère en masse et au moins une fraction polymère active en surface, cette dernière fraction étant (a) fixée de façon covalente à la ou aux fraction(s) polymère(s) en masse ou mélangée à celle(s)-ci, et (b) présente en quantité suffisante pour conférer à la ou aux région(s) polymère(s) une énergie de surface critique comprise entre 20 dynes/cm et 30 dynes/cm après l'implantation ou l'insertion du dispositif dans le sujet.

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