Implantable polymeric device for sustained release of...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 9/00 (2006.01) A61L 31/16 (2006.01) A61P 25/36 (2006.01)

Patent

CA 2487577

The present invention provides compositions, methods, and kits for treatment of opiate addiction and pain. The invention provides a biocompatible nonerodible polymeric device which releases buprenorphine continuously with generally linear release kinetics for extended periods of time. Buprenorphine is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with buprenorphine.

La présente invention concerne des compositions, des procédés et des trousses conçus pour traiter une toxicomanie aux opiacés et la douleur. Cette invention concerne un dispositif polymère non érodable biocompatible qui libère de la buprénorphine de manière continue avec une cinétique de libération généralement linéaire pendant de longues périodes de temps. La buprénorphine est libérée par des pores qui s'ouvrent à la surface de la matrice polymère dans laquelle elle est encapsulée. Ce dispositif peut être administré par voie sous-cutanée à un individu nécessitant un traitement continu à la buprénorphine.

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