Imprinting a substrate for separation of a target molecule...

C - Chemistry – Metallurgy – 08 – J

Patent

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Details

C08J 5/24 (2006.01) B01D 57/00 (2006.01) B01J 20/30 (2006.01) B01J 20/32 (2006.01) C08J 7/04 (2006.01) G01N 33/543 (2006.01) B01J 20/28 (2006.01)

Patent

CA 2495894

The present invention is directed to a method of producing a substrate suitable for separation of a target molecule from a fluid medium. This method includes providing an emulsion comprising a water phase in an oil phase, where the oil phase contains a polymerizable monomer and the water phase contains the target molecule. The substrate, having pores extending from one side of the substrate to another side of the substrate, is coated with the emulsion, and the monomer in the emulsion coated substrate is then polymerized. The water and target molecule are removed from the polymerized, emulsion coated substrate. As a result, the substrate is imprinted with the target molecule and, therefore, is suitable for separation of the target molecule from a fluid medium. The resulting article and its use are also disclosed.

La présente invention concerne un procédé de production d'un substrat convenant à la séparation d'une molécule cible d'un milieu liquide. Ce procédé consiste à utiliser une émulsion eau dans l'huile dont la phase huileuse renferme un monomère polymérisable et la phase aqueuse renferme la molécule cible. Le substrat, qui comporte des pores qui s'étendent d'un côté à un autre du substrat, est recouvert avec l'émulsion, puis, le monomère dans le substrat recouvert avec l'émulsion est polymérisé. Ensuite, l'eau et la molécule cible sont retirées du substrat polymérisé. Ainsi, le substrat comporte l'empreinte de la molécule cible et convient, par conséquent, à la séparation d'une molécule cible d'un milieu liquide. L'invention concerne également l'article résultant et son application.

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