Improved anti-trkb antibodies

Details Improved anti-trkb antibodies Improved anti-trkb antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2712298

The present invention provides improved antibodies or antigen-binding molecules that specifically recognize and agonize the tyrosine receptor kinase B (TrkB) receptor, and methods of their use. Also provided in the invention are polynucleotides and vectors that encode such molecules and host cells that harbor the polynucleotides or vectors.

L'invention concerne des anticorps améliorés ou molécules de liaison à un antigène qui reconnaissent et combattent spécifiquement le récepteur de tyrosine kinase B (TrkB), et des procédés pour leur utilisation. Il est également proposé des polynucléotides et des vecteurs qui codent de telles molécules et des cellules hôtes qui hébergent les polynucléotides ou vecteurs.

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