Improved antiandrogens

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 9/00 (2006.01) A61K 31/56 (2006.01) C07J 1/00 (2006.01) C07J 21/00 (2006.01) C07J 33/00 (2006.01) C07J 43/00 (2006.01) C07J 73/00 (2006.01)

Patent

CA 2136303

2136303 9426767 PCTABS00034 Androgen nucleus derivatives having specified substituents at the 17.alpha. position are disclosed for use as antiandrogens for the treatment of androgen-dependent diseases. In some preferred embodiments, the compound EM-250 is formulated together with pharmaceutically acceptable diluent or carrier for topical use in the treatment of androgen-dependent diseases associated with the skin.

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