Improved antibodies immunoreactive with heregulin-coupled her3

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) G01N 33/574 (2006.01) C07K 14/485 (2006.01)

Patent

CA 2759792

Antibodies which specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer.

L'invention concerne des anticorps qui se lient spécifiquement à HER3 couplé héréguline, au niveau d'un site distinct du site de liaison de héréguline. Ces anticorps sont particulièrement utiles dans le traitement du cancer.

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