Improved antibody-enzyme direct conjugates and method of...

Details Improved antibody-enzyme direct conjugates and method of... Improved antibody-enzyme direct conjugates and method of...

C - Chemistry, Metallurgy

12

N

C12N 9/96 (2006.01) G01N 33/535 (2006.01)

Patent

CA 2076347

A direct antibody-enzyme conjugate which enzyme to antibody ratio is approximately 3. The method of producing the di- rect antibody-enzyme conjugate comprises adding sulfhydral groups to the antibody and maleimide groups to an enzyme and then conjugating the so-modified antibody and enzyme.

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