A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/68 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2194168
A solid or semi-solid bioadherent, orally ingestible drug delivery system containing a water-in-coil system having at least two phases, one phase comprises from about 25 % to about 75 % by volume of an internal hydrophilic phase and the other phase comprises from about 25 % to to about 75 % by volume of an external hydrophobic phase wherein the external hydrophobic phase is comprised of three components: a) an emulsifier, b) a glyceride ester and c) a wax material.
La présente invention concerne un système d'administration de médicaments bioadhérents solides ou semi-solides, oralement ingérables. Il se compose d'un système eau-dans-l'huile présentant au moins deux phases. Une phase comporte un volume de 25 % à 75 % de phase hydrophile interne, et l'autre phase comporte un volume de 25 % à 75 % de phase hydrophobe externe. La phase hydrophobe externe est constituée de trois composants: a) un émulsifiant, b) un ester de glycéride et c) une substance cireuse.
Cuca Robert C.
Kirschner Mitchell I.
Levinson R. Saul
Lienhop Keith S.
Riley Thomas Charles Jr.
Borden Ladner Gervais Llp
Kv Pharmaceutical Company
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