Improved biological insect control agents and methods of use

Details Improved biological insect control agents and methods of use Improved biological insect control agents and methods of use

C - Chemistry, Metallurgy

12

N

167/140, 195/39,

C12N 15/54 (2006.01) A01N 63/00 (2006.01) C07K 14/575 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 9/10 (2006.01) C12N 9/16 (2006.01) C12N 15/00 (2006.01) C12N 15/82 (2006.01) C12N 15/866 (2006.01)

Patent

CA 2033169

Insect control agents comprising genes encoding proteins affecting the growth, development or behavior of an insect are provided. The gene is either activated to prevent insect molting and pupation or is inactivated to reduce the feeding behavior, inhibit growth and result in the earlier death of the insect host. Such an insect control agent is exemplified by a baculovirus in which the gene encoding ecdysteriod glucosyltransferase has been inactivated. Additionally, such baculoviruses may be further modified to express a protein which affects ecdysis. Methods for producing the insect control agent and methods of controlling insects by exposing them to the insect control agent are also included.

L'invention concerne des insecticides comprenant des gènes codant des protéines affectant la croissance, le développement ou le comportement d'un insecte. Le gène est soit activé pour empêcher la mue et la pupaison des insectes soit inactivé pour réduire le comportement alimentaire, inhiber la croissance et entraîner la mort précoce de l'hôte de l'insecte. L'exemple d'un tel insecticide est un baculovirus dans lequel le gène codant la glucosyltransférase ecdystériode a été inactivé. De plus, de tels baculovirus peuvent être encore modifiés pour exprimer une protéine qui affecte l'ecdysie. Des procédés de production d'un tel insecticide et des procédés de lutte contre des insectes en les exposant à cet insecticide sont également décrits.

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