Improved biosensor

G - Physics – 01 – N

Patent

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Details

G01N 27/327 (2006.01) G01N 27/333 (2006.01)

Patent

CA 2294082

The present invention provides a membrane based biosensor. The biosensor includes an electrode and a passivating layer bound to the electrode. A lipid membrane incorporating ionophores, the conductivity of the membrane being dependent on the presence or absence of an analyte, is bound to the passivating layer in a manner such that an ionic reservoir exists between the membrane and the passivating layer. Reservoir spanning molecules spanning the ionic reservoir are also included. These molecules are covalently attached at one end to the membrane and at the other to the passivating layer. The incorporation of this passivating provides greater stability to the sensor.

L'invention concerne un biocapteur à base de membrane, qui comprend une électrode et une couche de passivation liée à l'électrode. Une membrane lipidique comprenant des ionophores, la conductivité de la membrane dépendant de la présence ou de l'absence d'un analyte, est liée à la couche de passivation de manière qu'un réservoir ionique soit présent entre la membrane et la couche de passivation. Des molécules recouvrant le réservoir ionique sont également prévues. Ces molécules sont fixées de manière covalente à une extrémité de la membrane et par l'autre par une couche de passivation. L'addition de cette passivation confère une meilleure stabilité au capteur.

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