Improved chondrogenic differentiation of human mesenchymal...

Details Improved chondrogenic differentiation of human mesenchymal... Improved chondrogenic differentiation of human mesenchymal...

A - Human Necessities

61

K

A61K 35/28 (2006.01) A01N 1/02 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2274122

Disclosed are a composition of chemically defined components having elevated levels of simple sugars which support the enhanced in vitro chondrogenesis of mesenchymal progenitor cells, a method for in vitro chondrogenic induction of such progenitor cells and a method of forming human chondrocytes in vitro from such progenitor cells.

La présente invention concerne une composition de composants chimiquement définis caractérisés par des niveaux élevés en sucres simples et permettant d'améliorer la chondrogénèse in vitro des cellules progénitrices du mésenchyme. L'invention concerne également un procédé d'induction in vitro de la chondrogénèse de telles cellules progénitrices et un procédé de formation in vitro de chondrocytes humains.

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