Improved composition for collecting and preserving placental...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2633980

The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.

La présente invention concerne des compositions améliorées et des procédés pour la collecte de cellules souches à partir d'un organe, par exemple le placenta. L'invention concerne une composition de collecte de cellules souches comprenant un inhibiteur de l'apoptose et, éventuellement, une enzyme telle qu'une protéase ou une enzyme mucolytique, un vasodilatateur, un inhibiteur de nécrose, un perfluorocarbone transporteur d'oxygène ou un composé de préservation d'organes. L'invention concerne des procédés d'utilisation de la composition de collecte de cellules souches pour collecter des cellules souches et pour préserver les populations de cellules souches.

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