Improved controlled release dosage form including a banded...

Details Improved controlled release dosage form including a banded... Improved controlled release dosage form including a banded...

A - Human Necessities

61

K

A61K 9/00 (2006.01)

Patent

CA 2540044

The present invention includes a dosage form configured to provide the controlled release of an active agent formulation. A dosage form according to the present invention includes a reservoir containing an active agent formulation and an engine positioned at least partially within the reservoir. In order to reduce the possibility that the engine included in a dosage form of the present invention will separate from the reservoir either during or after fabrication, the dosage form of the present invention includes a band that binds the engine to the reservoir. The band is provided over an outside surface of the both the engine and the reservoir at or near the interface formed where the engine enters the opening provided in the reservoir. The present invention also includes a method of fabricating controlled release dosage forms having banded engine.

L'invention concerne une forme posologique configurée pour assurer la libération contrôlée d'une formulation d'agent actif. Selon l'invention, la forme posologique comprend un réservoir contenant une formulation d'agent actif et un moteur disposé au moins partiellement à l'intérieur du réservoir. Afin de réduire le risque de séparation du moteur compris dans la forme posologique de la présente invention et du réservoir pendant ou après la fabrication, la forme posologique de la présente invention comprend une bande qui lie le moteur au réservoir. La bande est ménagée par-dessus une surface externe du moteur et du réservoir, à la hauteur ou près de la jonction formée lors de l'introduction du moteur dans le réservoir. La présente invention comprend un procédé de fabrication de formes posologiques à libération contrôlée comprenant un moteur attaché.

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