Improved cross-linked compositions

Details Improved cross-linked compositions Improved cross-linked compositions

C - Chemistry, Metallurgy

08

L

C08L 89/06 (2006.01) C08H 1/06 (2006.01) C08J 9/30 (2006.01)

Patent

CA 2728187

Improved compositions comprising a cross--linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and preferably prepared in a non-phosphate buffer solvent. Optionally and preferably, the cross-linkable protein includes gelatin and any gelatin variant or variant protein as described herein. Optionally and preferably, the non-toxic material comprises transglu-taminase (TG), which may optionally comprise any type of calcium dependent or independent transglutaminase, which may for example optionally be a microbial transglutaminase (mTG).

L'invention concerne des compositions améliorées comprenant une protéine ou un polypeptide réticulable, et une matière non toxique qui induit la réticulation de la protéine réticulable. Les compositions sont éventuellement et de préférence préparées dans un solvant tampon non phosphate. Eventuellement et de préférence, la protéine réticulable comprend de la gélatine et un variant de gélatine quelconque ou une protéine de variant, comme il est décrit dans la description. Eventuellement et de préférence, la matière non toxique comprend de la transglutaminase qui peut éventuellement comprendre un type quelconque de calcium dépendant ou indépendant de la transglutaminase qui peut par exemple éventuellement être une transglutaminase microbienne (mTG).

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