Improved crystal structure

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/12 (2006.01) A61K 31/135 (2006.01) C07D 451/06 (2006.01) C07H 3/04 (2006.01)

Patent

CA 2325551

A process for the production of crystals with controlled surface smoothness, size, shape and degree of crystallinity, compositions comprising such crystals, and the use of certain crystals, especially lactose, lactose monohydrate, fluticasone propionate, salmeterol xinafoate, salbutamol sulphate or ipratropium bromide in pharmaceutical compositions.

L'invention porte sur un procédé de production de cristaux dont la rugosité superficielle, la taille, la forme et le degré de cristallinité peuvent être modulés, sur des compositions les contenant, et sur l'utilisation de certains cristaux, en particulier de lactose, de monohydrate de lactose, de propionate de fluticasone, de xinafoate de salmétérol, de sulfate de salbutamol ou de bromure d'ipratropium dans des préparations pharmaceutiques.

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