A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/06 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2742449
The present invention relates to a method for the preparation of a tablet comprising at least 50% w/w of calcium carbonate, the method comprising i) providing a particulate composition comprising a) calcium carbonate, b) a binding sugar alcohol selected from sorbitol or isomalt, or combinations thereof, c) a non-binding sugar alcohol selected from mannitol, maltitol or xylitol, or combinations thereof, and ii) compressing said composition using a tabletting machine equipped with at least one pair of punches and dies, wherein the pair of punches and die before filling the die with said particulate composition is sprayed with a composition comprising a lubricant selected from magnesium stearate, calcium stearate or stearic acid or combinations thereof.
L'invention porte sur un procédé de préparation dun comprimé comportant au moins 50% p/p de carbonate de calcium. Le procédé consiste: i) à élaborer une composition particulaire comprenant a) du carbonate de calcium, b) un alcool de sucre liant sélectionné parmi le sorbitol ou lisomalt, ou leurs combinaisons, c) un alcool de sucre non liant sélectionné parmi le mannitol, le maltitol ou lxylitol, ou leurs combinaisons; ii) à comprimer ladite composition à l'aide dune machine à comprimés présentant au moins une paire de poinçon et de matrice, la matrice, avant dêtre remplie de ladite composition, recevant une pulvérisation de lubrifiant sélectionné parmi du stéarate de magnésium, du stéarate de calcium ou de lacide stéarique ou leurs combinaisons.
Aage Henrik Ravn
Bertelsen Poul Egon
Olsen Peder Mohr
Thisted Thomas
Nycomed Pharma As
Sim & Mcburney
LandOfFree
Improved dissolution stability of calcium carbonate tablets does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Improved dissolution stability of calcium carbonate tablets, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Improved dissolution stability of calcium carbonate tablets will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1568510