Improved dosing regimen of temozolomide for treating cancer...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4188 (2006.01) A61K 38/18 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2585446

The use of temozolomide for the manufacture of a medicament for treating cancer in a patient in need of such treating is disclosed comprising administering temozolomide according to improved dosing regimen and/or schedules based on the patient's MGMT level. Additional improved dosing regimen and/or schedules for treating patients with temozolomide are also dislosed.

L'invention concerne des méthodes pour traiter un cancer chez un patient nécessitant un tel traitement. Ces méthodes consistent à administrer du témozolomide selon un schéma posologique et/ou des ordonnancements améliorés fondés sur le niveau de MGMT (O6-méthyle guanine-ADN méthyltransférase) du patient. L'invention concerne également des méthodes améliorées pour traiter des patients à l'aide de témozolomide.

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