Improved flexible collodion compositions

A - Human Necessities – 61 – K

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Details

A61K 31/60 (2006.01) A61K 9/70 (2006.01) A61K 7/04 (1990.01) A61L 25/00 (1990.01)

Patent

CA 2101083

Film-forming flexible collodion compositions can be improved by including one or more topically acceptable polymers in an amount sufficient to increase the resilience of the film formed. Suitable polymers include polyalkylenes and (meth)acrylate homo- or copolymers. Preferred embodiments include isobutylene-butene copolymer and/or polymethyl methacrylate. The compositions can further include salicylic acid and a topically acceptable crystallization inhibitor in an amount sufficient to suppress the crystallization of dissolved salicylic acid from the composition. Suitable crystallization inhibitors include at least one mono- or polyester and/or ether. Preferred embodiments include a mixture of ethyl lactate and castor oil, and ethyl lactate alone. The compositions preferably also contain a local anesthetic.

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