Improved immunoassay methods

Details Improved immunoassay methods Improved immunoassay methods

G - Physics

01

N

G01N 33/557 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2663154

The invention generally relates to the field of diagnostic or prognostic assays and in particular relates to assays for the detection of antibodies in a sample comprising patient bodily fluid, wherein such antibodies are used as biological markers of a disease state or disease susceptibility. The assay is based on cross-titration of both the patient bodily fluid to be tested for the antibody and an antigen used to detect the antibody by specific binding.

L'invention concerne en général le domaine des dosages pronostiques et diagnostiques et en particulier des dosages permettant de détecter des anticorps dans un échantillon comprenant du fluide corporel, lesdits anticorps étant utilisés comme marqueurs biologiques d'un état pathologique ou d'une prédisposition à une maladie. Le dosage est basé sur le titrage croisé entre le fluide corporel à tester pour l'anticorps et un antigène utilisé pour détecter l'anticorps au moyen d'une liaison spécifique.

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