Improved influenza vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/145 (2006.01)

Patent

CA 2632483

The present invention relates in general to influenza vaccines for human and veterinary use. In particular, the present invention provides a vaccine able to effect long term and cross-strain protection comprising at least two influenza virus epitopes expressed as aa chimeric polypeptide wherein at least one epitope is influenza A virus matrix protein epitope and the second epitope is a haemagglutinin peptide epitope.

La présente invention concerne généralement des vaccins contre la grippe pour utilisation humaine et vétérinaire. En particulier, la présente invention concerne un vaccin capable de produire une protection à long terme multisouche comprenant au moins deux épitopes de virus contre la grippe exprimés sous la forme d'un polypeptide chimère où au moins un épitope est un épitope de protéine de matrice du virus de la grippe A et le second épitope est un épitope de peptide d'hémagglutinine.

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