Improved medicinal compositions comprising buprenorphine and...

A - Human Necessities – 61 – K

Patent

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A61K 45/06 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2678675

There is provided a composition for the treatment of pain in human patients wherein said composition comprises buprenorphine to naloxone in a ratio by weight of from 2.1:1 to 8:1, the amount of buprenorphine and naloxone being suitable to provide analgesia, the composition being in a transdermal or transmucosal dosage form. Also provided are an associated method and use.

L'invention porte sur une composition destinée au traitement de la douleur chez des patients humains, ladite composition comprenant de la buprénorphine et de la naxolone selon un rapport en poids compris entre 2,1:1 et 8:1, la quantité de buprénorphine et de naloxone étant apte à produire une analgésie, la composition se présentant sous une forme posologique transdermique ou transmucosale. L'invention concerne également un procédé et une utilisation associés.

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