Improved method for eradication of helicobacter pylori

A - Human Necessities – 61 – K

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Details

A61K 31/438 (2006.01) A61K 31/43 (2006.01) A61K 31/4439 (2006.01) A61K 31/65 (2006.01) A61K 33/24 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2330424

The invention provides methods for the treatment and/or prevention of recurrence of a gastrointestinal disorder associated with Helicobacter pylori in a patient requiring said treatment and/or prevention, which comprise administering to the patient a therapeutically effective amount of a first antibiotic which is an ansamycin and a therapeutically effective amount of at least a second antibiotic or antimicrobial agent. The invention also provides pharmaceutical compositions for use in the methods of the invention.

L'invention concerne des méthodes de traitement et/ou de prévention de la récurrence d'un trouble gastro-intestinal associé à helicobacter pilori chez un patient nécessitant ledit traitement et/ou ladite prévention. Ladite méthode consiste à administrer au patient une dose efficace au plan thérapeutique d'un premier antibiotique constituant une ansamycine, et une dose efficace au plan thérapeutique d'au moins un deuxième antibiotique ou agent antimicrobien. L'invention porte également su des compositions pharmaceutiques à utiliser dans les méthodes de l'invention.

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